The DRIFT Study

About the Study

The DRIFT Study is being led by the Division of Orthopaedic Surgery at Ann & Robert H. Lurie Children’s Hospital of Chicago along with the Infrastructure for Musculoskeletal Pediatric Acute Care Trials (IMPACCT) consortium.

Study locations

  • IWK Health Centre
  • The Hospital for Sick Children

  • Boston Children’s Hospital
  • Rutgers University
  • Albert Einstein College of Medicine
  • Hospital for Special Surgery
  • Nemours Alfred I. duPont Hospital for Children
  • University of Rochester
  • New York University Grossman School of Medicine

  • Mississippi Children's Hospital
  • Duke University
  • All Children's Johns Hopkins
  • The University of North Carolina Chapel Hill
  • Children’s Hospital New Orleans
  • Nicklaus Miami Children’s

  • The University of Texas Southwestern Medical Center / Texas Scottish Rite Hospital for Children
  • Phoenix Children’s Hospital
  • Baylor College of Medicine/Texas Children's Hospital
  • UNM Carrie Tingley

  • Children’s Hospital Los Angeles
  • The Regents of University of California, Los Angeles
  • Oregon Health & Science University
  • Board of Trustees of the Leland Stanford Junior University
  • Seattle Children’s Hospital

  • Gillette Children’s Specialty Healthcare / Children’s Minnesota
  • Indiana University/ Riley Children's Hospital
  • Cincinnati Children’s Hospital Medical Center
  • The Children’s Hospital of Philadelphia
  • Johns Hopkins Medicine
  • University of Iowa
  • Ann & Robert H. Lurie Children’s Hospital
  • Case Western Reserve University/Rainbow Babies
  • HealthPartners Institute/TRIA

Information about the Study

Study Design

DRIFT is a multicenter, prospective randomized superiority trial comparing functional outcomes between children treated with sedated reduction versus no formal reduction.

Treatments

Reduction and nonreduction treatment of displaced pediatric distal radius fractures (Peds-DRIFT Trial - Distal Radius Interventions for Fracture Treatment).

Things to Know

Despite studies of distal radius fractures dating back more than 200 years, doctors are not sure which treatment is better.

PROMIS

The primary objective of this study is to determine if reduction treatment results in superior upper extremity function compared with non-sedated casting at 1 year.

Participant Data

Study participant research data, which is for purposes of statistical analysis and scientific reporting, will be transmitted to and stored at the Duke Clinical Research Institute (DCRI).

Study Funders

The study is funded by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) and the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD).

Principal Investigators

Joseph Janicki, MD MS, Lurie Children’s

Joseph Janicki, MD, MS, (Principal Investigator) is an Associate Professor of Orthopaedic Surgery at Northwestern University and has an MS in Clinical Investigation (Northwestern). Dr. Janicki is a surgeon-scientist whose research includes bone health in children, hip dysplasia and multicenter research (4 topic specific study groups). He is currently the PI of a 19 site PROOF trial examining children’s open fracture treatment. Dr. Janicki will serve as the PI for the IMPACCT study and will be responsible for study protocols, funding, and management.

Jamie Burgess, PhD., Lurie Children’s

Jamie Burgess, PhD, (Co-Investigator) is a Research Assistant Professor at Northwestern University whose research focuses on increasing efficiency in multicenter trials in pediatric orthopaedics, operationalizing informed consent and evaluating educational tools for clinical research. She has served as the lead research manager on two multicenter, international studies in pediatric orthopaedics.

James Wright, MD, SickKids

James Wright, MD, (Co-Investigator) is Senior Scientist and former program head of the Child Health Evaluation Sciences (CHES) Program at The Hospital for Sick Children. He is a Professor of Surgery, Health Policy, Management, and Evaluation at the University of Toronto and is adjunct Professor at University of Oxford and CoI in UK trial. He has led many RCTs. He was the inaugural Associate Editor for Evidence-based Orthopaedics for the Journal of Bone and Joint Surgery. He has been supported for 20 years by the Canadian Institutes for Health Research (CIHR) (US Canadian equivalent of NIH).

Andrew Georgiadis, MD, Gillette Children’s

Andrew G. Georgiadis MD is a native of Ohio and pediatric orthopaedic surgeon at Gillette Children's Hospital in St. Paul, Minnesota. He performed residency training at Henry Ford Hospital in Detroit, Michigan, followed by fellowships in pediatric orthopaedics at the Children's Hospital of Philadelphia and the Royal Children's Hospital in Melbourne, Australia. His clinical interests include pediatric orthopaedic trauma, the treatment of children with cerebral palsy, instrumented gait analysis, and limb lengthening and deformity correction.

Walter Truong, MD, Gillette Children’s

Dr. Walter Truong attended medical school at Ohio State University before completing his residency in Orthopaedic Surgery at the University of Minnesota. He spent his fellowship year at the Hospital for Sick Children in Toronto where he obtained a Certificate from the University of Toronto in Pediatric Orthopaedic Surgery. Walter enjoys returning children to optimal health and function after orthopaedic trauma and has a special interest in scoliosis treatment and orthopedic needs for children with neuromuscular, genetic, complex and rare conditions.

Study Team

The research team for the DRIFT study has a lot of experience in caring for patients with fracture injuries and are active in health research.

Jacob Wild, BS

Jacob Wild is a Clinical Research Professional. He has worked with the Division of Orthopaedic Surgery at Ann & Robert H. Lurie Children’s Hospital of Chicago since 2015. His efforts have primarily been associated with pediatric sports specialization and concussion. He will be supporting the IMPACCT Consortium. In his spare time, he enjoys scuba diving, skiing, and playing golf.

Lauren Spirov, MS BS

Lauren has been with Lurie Children's for three years and supports both Sports Medicine studies and Orthopedic studies. She primarily supports knee injury studies and is the program coordinator for the Institute of Sports Medicine Knee Injury Prevention Program (KIPP).

Daniel McBride, BS

Daniel McBride is a Clinical Research Coordinator I at Lurie Children’s Hospital of Chicago under the Department of Orthopaedic Surgery and Sports Medicine. He supports the research studies of 5 physician investigators. In his spare time, he enjoys powerlifting, Brazilian jiu-jitsu, guitar, and enjoying different foods around the city of Chicago.

Delanie Rybacki, BS

Delanie is a clinical research coordinator, working on multiple studies, including IMPACCT. She has been a part of the Lurie Children's team since March of 2022. Outside of work, Delanie enjoys running, spending time at the lake, and exploring new restaurants in the Chicago area.

Candace Young, BS

Candace is the Project Manager for IMPACCT within the Division of Orthopaedic Surgery and Sports Medicine at Ann & Robert Children’s Hospital of Chicago since June 2022. She is an advocate for increasing minority participation in clinical research to address health disparities within research. In her spare time, she enjoys exploring a variety of cultural restaurants in Chicago, listening to music/attending music festivals, and traveling.